Contamination of coagulation tests with heparin from blood gas samples
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منابع مشابه
Contamination of coagulation tests with heparin from blood gas samples.
We investigated the possibility that samples of blood could be contaminated by heparinized blood gas syringes, giving spurious results in coagulation tests. We collected coagulation test samples before (n=5) and after (n=13) blood gas sampling from a venous cannula in a volunteer. The results of activated partial thromboplastin time (APTT) tests were compared between control samples and samples...
متن کاملy the use of heparin in preparing samples for blood - gas analysis
16 October 2007 ■ MLO www.mlo-online.com T he significance of good practice during the pre-testing phase of clinical-laboratory investigation cannot be overemphasized. The production of high-quality, accurate results, which are clinically useful, depends as much on practice before the patient’s sample reaches the laboratory as it does on the analytical phase within the laboratory. There are few...
متن کاملThe use of heparin in preparing samples for blood-gas analysis.
Heparin is the only anticoagulant used to prepare samples for blood-gas analysis. There are two ways in which heparin can interfere with results. The first is high heparin concentration in blood, and the second is heparin dilution of blood if liquid rather than dried (lyophilized) heparin is used. Traditional blood-gas analytes (pH, pCO2, and pO2) are less affected than electrolytes (particular...
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Heparin is unique as one of the oldest drugs currently still in widespread clinical use as an anticoagulant, a natural product, one of the first biopolymeric drugs, and one of the few carbohydrate drugs. Recently, certain batches of heparin have been associated with anaphylactoid-type reactions, some leading to hypotension and death. These reactions were traced to contamination with a semi-synt...
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T HE MECHANISMS responsible for the maintenance of hemostasis on the level of terminal blood vessels are only partially understood. Although platelets have a major role in preventing or arresting hemorrhages from small vessels, clinical and experimental evidence suggests that other factors may also be involved. The role of blood coagulation products or components requires further elucidation, a...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2001
ISSN: 0007-0912
DOI: 10.1093/bja/87.4.628